Printer friendly
"AcronymAttic.com

What does C>p stand for?

C>p stands for 2',3'-cyclic phosphate

This definition appears rarely

Samples in periodicals archive:

The presence of 2’-OH group on the ribose sugar makes it susceptible to nucleophilic attack in the presence of OH (ions) on the 5’-phosphorous atom, thus causing breakage of the phosphodiester link and forming a 2,’3’ cyclic phosphate.
1. 27. 1) Catalyzes the two-stage endonucleolytic cleavage of RNA to yield nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending mainly in Gp. In the reaction, cleavage occurs between the 3'-phosphate group of a guanidine ribonucleotide and 5'-hydroxyl of the adjacent nucleotide. The initial product is a 2':3' cyclic phosphate.
[1] There is a transition state (shown above), where the phosphorus is bonded to five oxygen atoms. [2] The phosphorus then detaches from the oxygen connecting it to the adjacent sugar, resulting in ester cleavage of the RNA backbone. (This mechanism is also referred to as RNA cleavage. ) This produces a 2’,3’-cyclic phosphate that can then yield either a 2’- or a 3’-nucleotide when hydrolyzed. This process is shown in Figure 1.
Adenosine 2',3'-cyclic monophosphate.
3. 1 and N-3. 3. 2). A 2':3'-cyclic phosphate residue may be indicated by > or >p. [See however Addendum] Comments i) The terminal p's should be specified unless their presence is unknown, in doubt, or of no significance to the argument. ii) "Polarity" (direction other than 3'→5') is dealt with in N-3.
In viral DNA, some bases may be hydroxymethylated or glucosylated. In RNA, minor or modified bases occur more frequently. Some examples include hypoxanthine, dihydrouracil, methylated forms of uracil, cytosine, and guanine, as well as modified nucleoside pseudouridine. [3] Nucleotides with phosphate groups in positions other than on the 5' carbon have also been observed. Examples include ribonucleoside 2',3'-cyclic monophosphates.
Adenosine 2',3'-cyclic monophosphate.