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What does L:N stand for?

L:N stands for Lesion-to-normal

This definition appears rarely

Samples in periodicals archive:

In clinical studies employing planar imaging techniques, more QUADRAMET® accumulates in osteoblastic lesions than in normal bone with a lesion-to-normal bone ratio of approximately 5. The mechanism of action of QUADRAMET® in relieving the pain of bone metastases is not known.
This is probably because about 30-75% of the bone mineral content must be lost before a metastasis is evident on a radiograph [11]. In contrast, as little as a 5-10% change in the ratio of the lesion to normal bone is required to detect an abnormality on bone scan [11]. The sensitivity for bone scan in detecting bone metastases is between 62% - 100% [11].
Quadramet® (samarium Sm-153 EDTMP) has an affinity for bone and concentrates in areas of bone turnover in association with hydroxyapatite. In clinical studies employing planar imaging techniques, more Quadramet® accumulates in osteoblastic lesions than in normal bone with a lesion-to-normal bone ratio of approximately 5. The mechanism of action of Quadramet® in relieving the pain of bone metastases is not known.