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Central imidazoline (I1) receptors as targets of centrally acting antihypertensives: moxonidine and rilmenidine. van Zwieten PA1.
Conclusions: These results suggest that the hypotension and bradycardia induced by intravenous administration of moxonidine and rilmenidine were mediated mainly by actions on central imidazoline.
Publication » Central Imidazoline- and alpha2-Receptors Involved in the Cardiovascular Actions of Centrally Acting Antihypertensive Agentsa.